Immune Allen10 2900genes
| PAG Title | Immune Allen10 2900genes |
| PAG ID | FEX001138 |
| Type | G |
| Source Link |  GeneSigDB |
| Publication Reference | |
| PAG Description | SuppTable 1. LCH CD207 vs Control Skin CD207 - Expression Array Results (LCH CD207/Skin CD207). Langerhans cell histiocytosis (LCH) is a rare disease characterized by heterogeneous lesions containing CD207+ Langerhans cells (LCs) and lymphocytes that can arise in almost any tissue and cause significant morbidity and mortality. After decades of research, the cause of LCH remains speculative. Results from this study support a model of LCH pathogenesis in which lesions do not arise from epidermal LCs but from accumulation of bone marrow-derived immature myeloid dendritic cells that recruit activated lymphocytes. |
| Species | Homo sapiens |
| nCoCo Score | 1 |
| Base PAG ID | FEX001138 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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